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Paper Abstract and Keywords
Presentation 2022-07-22 16:20
Image Classification of Cancer Cells Treated with IRDAptermer
Rahman Rawnak Mim, Yuuka Yamagata, Yoshiro Chuman, Shogo Muramatsu (Niigata Univ.)
Abstract (in Japanese) (See Japanese page) 
(in English) This work evaluates convolutional neural network (CNN)-based image classifiers for determining the effect of a cell membrane-permeable DNA aptamer molecule, IRDAptamer, on cancer cells. The purpose of this study is to automate the classification of whether DNA aptamers, which are fragments of DNA, have reached the nucleus of cancer cells from three types of images. The three types of images are phase images of cells, fluorescent images of cell nuclei, and fluorescent images of drugs. It is proposed to form three-channel images of these three types of images as multimodal information and to design a classifier for their screening by transfer learning of existing CNNs. It is expected to contribute to rapid screening in the development of future drug discovery. In this study, the authors construct CNNs for classification by various data augmentation and transfer learning of various CNNs and evaluate the effectiveness of each method by comparing their accuracies.
Keyword (in Japanese) (See Japanese page) 
(in English) Visual screening / Multimodal images / CNN / VGG16 / VGG19 / ResNet50V2 / Inception V3 / Image Classification  
Reference Info. ITE Tech. Rep., vol. 46, no. 20, ME2022-70, pp. 23-26, July 2022.
Paper # ME2022-70 
Date of Issue 2022-07-15 (ME) 
ISSN Print edition: ISSN 1342-6893    Online edition: ISSN 2424-1970
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Conference Information
Committee ME  
Conference Date 2022-07-22 - 2022-07-22 
Place (in Japanese) (See Japanese page) 
Place (in English) Online 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To ME 
Conference Code 2022-07-ME 
Language English 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Image Classification of Cancer Cells Treated with IRDAptermer 
Sub Title (in English)  
Keyword(1) Visual screening  
Keyword(2) Multimodal images  
Keyword(3) CNN  
Keyword(4) VGG16  
Keyword(5) VGG19  
Keyword(6) ResNet50V2  
Keyword(7) Inception V3  
Keyword(8) Image Classification  
1st Author's Name Rahman Rawnak Mim  
1st Author's Affiliation Niigata University (Niigata Univ.)
2nd Author's Name Yuuka Yamagata  
2nd Author's Affiliation Niigata University (Niigata Univ.)
3rd Author's Name Yoshiro Chuman  
3rd Author's Affiliation Niigata University (Niigata Univ.)
4th Author's Name Shogo Muramatsu  
4th Author's Affiliation Niigata University (Niigata Univ.)
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Speaker Author-1 
Date Time 2022-07-22 16:20:00 
Presentation Time 30 minutes 
Registration for ME 
Paper # ME2022-70 
Volume (vol) vol.46 
Number (no) no.20 
Page pp.23-26 
Date of Issue 2022-07-15 (ME) 

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