We have developed 1.12um cell size low-noise front side illumination (FSI) CMOS image sensor with light pipe: SmartFSI®. Adopting unique bended light pipe structure, and optimizing cell layout and potential profile in photo diode, we realized quite high quantum efficiency (QE) of 72% and low read-out noise of 0.9ele, which exceeds the performance of backside illumination (BSI) image sensors.